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The most complete bioinformatics algorithm processor in the world!



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Whitehead Institute MIT, Stanford University, Wellcome Trust Sanger Institute,
European Bioinformatics Institute(EMBL), Roche, Incyte, Japan Patent Office, Affymetrix, 3M µîÀ» ºñ·ÔÇÑ ¸¹Àº ¿¬±¸±â°üµéÀº ÀÌ¹Ì DeCypher¸¦ »ç¿ëÇϰí ÀÖ½À´Ï´Ù.

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TimeLogic»ç°¡ °³¹ßÇÑ DeCypher´Â FPGA(Field Programmable Gate Array) reconfigurable Çϵå¿þ¾î ±â¼úÀ» »ç¿ëÇÏ¿©, ´Ù¾çÇÑ ¾Ë°í¸®ÁòÀ» ÃÖ°íÀÇ ½ºÇǵå·Î ÀÌ¿ëÇÒ ¼ö ÀÖ°Ô ÇØ µå¸²À¸·Î½á, ´Ù¸¥ ¾î¶² °¡¼Ó¿ë Åø(accelerator)º¸´Ùµµ ¶Ù¾î³­ ¼º´ÉÀ» À¯Áö½ÃÄÑ µå¸± ¼ö ÀÖ½À´Ï´Ù. ¶ÇÇÑ Çѹø ¼³Ä¡ÇÑ Çϵå¿þ¾îÀÇ ±³Ã¼ ¾øÀ̵µ, »õ·Î¿î ¾Ë°í¸®ÁòÀÌ ³ªÅ¸³¯ ¶§ ¸¶´Ù À̸¦ Àû¿ëÇÒ ¼ö ÀÖ´Â À¯¿¬¼ºÀ» Áö´Ï°í ÀÖ½À´Ï´Ù.



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DeCypher POWERED Algorithms

- Hardware Accelerated Tera-BLAST¢â includes ultra-fast BLASTN, BLASTP, BLASTX, TBLASTN,TBLASTX, and unique search parameters that extend speed and sensitivity vs. other BLAST implementations.

- Gene-BLAST¢â, intron spanning gapped Tera-BLAST for ultra-fast database searches, combined with dual-affine Smith-Waterman alignments. Includes reporting of sub-optimal alignments missed by Smith-Waterman.

- Hidden Markov Models, based on HMMer (Eddy). Includes J-State and Null2 processing. Of note: DeCypher is used at the Sanger Center for PFAM curation, and at the EBI for Interpro curation!

- HMM-Framesearch¢â (Birney: EstWise, EstSlim)

- Affine Smith-Waterman (in nucleic, protein, and translated versions), Dual-Affine Smith-Waterman¢â, Semi-Global Smith-Waterman¢â - uniquely designed for clustering and assembly applications

- Framesearch, Reverse-Framesearch

- ProfileSearch, ProfileScan & Profile Framesearch

- Symmetric Frame Independent¢â - a unique, symmetric form of Framesearch that spans insertion and deletion errors in both query and database texts simultaneously

- Tera-Clustering¢â Accelerated Clustering & Assembly

- Phrap, using performance improved SPS-PHRAP

- ClustalW, with graphical rendition of dendrogram via Java applet

- CPU-based NCBI BLAST, includes entire heuristic search suite: blastn, blastp, blastx, tblastn, tblastx

- NCBI PSI-BLAST