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DNA micro array

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bioinformatics systemÀ» Á¦°øÇØ µå¸³´Ï´Ù. ¿©±â¿¡´Â, microarray ½ÇÇèÀ» µðÀÚÀÎÇϰųª ALMA°¡ ƯÇ㸦 ÃëµæÇÑ ¹æ¹ýÀÎ SOTA clustering methodology¸¦ Æ÷ÇÔÇÕ´Ï´Ù.

JSOTA

Brief¡¦

This is BIOALMA¢¥s propietary clustering algorithm for microarray analysis. The Java Self-Organising Tree Algorithm (JSOTA), is a neural network that grows adopting the topology of a binary tree. The result of the algorithm is a hierarchical cluster obtained with the accuracy and robustness of a neural network. JSOTA clustering confers several advantages over classical clustering methods (see article).

More¡¦

JSOTA is an implementation of the JSOTA Algorithm that includes a window interface written in Java and the JSOTA core written in C++. This makes the program very easy to use whilst ensuring that the computationally-intensive part runs very fast. It is available for a wide range of platforms.
 










¡× JSOTA is a divisive method. The growing can be stopped at the desired hierarchical level.

¡× A criterion to stop the growing of the tree, based on the approximate distribution of probability obtained by randomisation of the original data set, is provided.

¡× Obtaining average gene expression patterns is a built-in feature of the algorithm.

¡× Since JSOTA runtimes are approximately linear with the number of items to be classified, it is especially suitable for dealing with huge amounts of data, making it possible to use the system on small computers.

¡× JSOTA can be applied to any data providing that they can be coded as a series of numbers and that a computable measure of similarity between data items can be used.

¡× JSOTA maps Gene Ontology data into the structure of clusters. You can test the power of the JSOTA algorithm by clicking on the next button



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almaZen System¨Ï

Brief info

almaZen System¨Ï is the only currently available that assists researchers in organizing, managing and analyzing the large number of biological samples involved in a typical DNA array experiment.

The system is bioalma's answer to the problem of management of the thousands of clones involved in the fabrication of a DNA microarray. The system incorporates a unique protocol, that allows storage of any type of information on a clone (accession numbers, identifiers, descriptions, images, text files, documents...) The accessing to the functional description of the clones and the recording of any incidences are trivial tasks with almaZen.

The system is oriented towards microtiter plates and includes several tools for storing, manipulating and annotating all relevant information relative to the sequences to be incorporated within the DNA microarray. Thanks to almaZen, identification of each spot on the microarray and review of all manipulations from its entry into the laboratory are easy and intuitive.

An important advantage of almaZen is that is a completely web-browser based application, with no software installation required on the client computer. A single almaZen license serves for an unlimited number of users!


















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almaZen System¨Ï Modules

PlateLogic
Plate Management
Stores all the relative information to its clones and multiwells in a quick and easy access database.

ArrayLogic
Array Management
Manages thousands of clones involved in the fabrication of a DNA array.

AnaLogic
Data Analysis
Allows the analysis of comparative microarray experiments and the tracking of all features from the slides to the original microtiter plates.

Other interesting features of almaZen System ¨Ï include:

¡× Microarray platform independent
Users can look up data from any workstation, even in their own home, as it is possible to access the system from any Web browser.

¡× Multi-user and multi-level access
Only authorized users are able to modify the content of the database.

¡× Minimum hardware requirements
Only a standard PC is required for fast results.

¡× Relational database-based system

¡× Easy Integration

Designed to facilitate integration of other external information on clones into system's database.

¡× Open and flexible system
Can be adapted to any DNA array laboratory.

Additional Content

To visualize an on-line demo of almaZen, please click next button


You may also want to download our PDF Documentation or Users Manual, describing almaZen's most powerful features


Detailed video info can be found here


To request a promotional almaZen Demo CD, please enter this section


Information Extraction

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